Chrome's a great browser, but it collects grime and buildup rather quickly. Most of us know that we should give it a quick cleaning every so often to keep it running smoothly, but most of us probably don't clear the cache often, which can result in decreased performance.
You could use an extension like Click & Clean to get the job done, but I'm always on the lookout for solutions that don't involve extensions, since they, too, can impact performance.
A general rule of thumb is that the fewer steps we have to take to do something, the likelier we are to do it, and cleaning out Chrome is no exception. So, instead of digging through Chrome's menu, just bookmark what you need to get faster access, and you'll be more apt to keep up with Chrome's minimal maintenance needs.
Chrome's cleaning settings can be found at "chrome://settings/clearBrowserData." Bookmark that address, and you can easily select it from the Omnibox's drop-down menu when typing, say, "clear." This works because Chrome prioritizes bookmarks in omnibox results, but, for obvious reasons, doesn't do so for settings.
You could take it a step further and add the setting as a search engine, using the same technique I use to launch boomarklets with a keyboard. Now, I can simply type "clean" into the omnibox (since that's what I chose as a keyword), press enter, and be taken directly to the page in question.
Of course, this works for any Chrome setting you want fast access to, so you could, for example, bookmark the 'add a user' page to quickly add users, or the fonts page to change your browser fonts.
The beauty of bookmarking, or adding a search engine, is the simplicity of Chrome's sync feature. Set it up once, and the setting will automagically appear in every future Chrome instance you install.
If you have a favorite Chrome tip, I'd love to hear about it in the comments.